Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 3.341


Transcription factors associated with FOS_FOS{B,L1}_JUN{B,D}.p2:

Gene SymbolEntrez IDGene Name
FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
FOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 8061 FOS-like antigen 1
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene



Activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2.

activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2


Sorted Z-values histogram for motif FOS_FOS{B,L1}_JUN{B,D}.p2

Sorted Z-values for motif FOS_FOS{B,L1}_JUN{B,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOS_FOS{B,L1}_JUN{B,D}.p2

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_116099648 9.956 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr7_-_135083906 7.486 NM_205855
FAM180A
family with sequence similarity 180, member A
chr16_+_56219802 7.242 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr19_-_40711034 6.927 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr5_+_150000394 6.654 NM_001109974
NM_007286
SYNPO

synaptopodin

chr1_+_17719405 6.641 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_181421984 6.369 LAMC2
laminin, gamma 2
chr6_+_31190505 6.122 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr2_+_169634330 5.593 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_-_94779727 5.461 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr6_-_138470160 5.388 NM_022121
PERP
PERP, TP53 apoptosis effector
chr12_-_68369322 5.347 NM_152439
BEST3
bestrophin 3
chr1_+_245646080 5.143 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr4_+_154397975 4.874 TRIM2
tripartite motif containing 2
chr17_-_36469869 4.744 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr17_-_37022465 4.685 NM_005557
KRT16
keratin 16
chr4_+_169989680 4.610 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr5_+_140848905 4.496 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr4_+_120276386 4.408 NM_016599
MYOZ2
myozenin 2
chr4_+_108965167 4.284 NM_001136258
SGMS2
sphingomyelin synthase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
Enrichment   P-value GO Accession GO Term
22.11 2.60e-02 GO:0031581 hemidesmosome assembly
14.48 2.30e-02 GO:0030574 collagen catabolic process
6.08 4.48e-07 GO:0008544 epidermis development
4.37 5.42e-03 GO:0001701 in utero embryonic development
3.87 2.15e-02 GO:0048568 embryonic organ development
3.42 4.66e-02 GO:0006954 inflammatory response
3.21 1.84e-02 GO:0043009 chordate embryonic development
3.18 2.15e-02 GO:0009792 embryo development ending in birth or egg hatching
3.16 2.32e-02 GO:0060429 epithelium development
3.13 1.76e-07 GO:0009888 tissue development
2.70 1.41e-02 GO:0009887 organ morphogenesis
2.52 1.91e-02 GO:0009790 embryo development
2.46 2.22e-03 GO:0009611 response to wounding
2.39 3.03e-03 GO:0042127 regulation of cell proliferation
2.04 4.40e-03 GO:0009653 anatomical structure morphogenesis
2.01 3.66e-04 GO:0048513 organ development
1.76 1.20e-04 GO:0048856 anatomical structure development
1.74 1.10e-03 GO:0048731 system development
1.65 2.69e-02 GO:0048518 positive regulation of biological process
1.59 2.49e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
14.31 2.74e-02 GO:0005922 connexon complex
3.59 6.29e-04 GO:0005578 proteinaceous extracellular matrix
3.37 4.71e-04 GO:0031012 extracellular matrix
2.25 9.53e-04 GO:0044421 extracellular region part
1.99 1.35e-05 GO:0005576 extracellular region
1.67 1.57e-02 GO:0044459 plasma membrane part
1.42 3.29e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
2.41 2.48e-02 GO:0005198 structural molecule activity